Statistical Analysis Methods

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The Kolmogorov-Smirnov Test

A real biological data example is presented in the image below: we examine the distances between PML locations and two other object types (RNA Polymerase II foci in different cell lines HT1080 and MRC5) with the goal of discovering whether there is a different functional role for the PML in the two cases.

Two sample KS example: EDFs for two sets of nearest neighbour distances

PML foci to RNA Polymerase II foci in two human cell lines (HT1080 and MRC5).

Plot indicates NO SIGNIFICANT DIFFERENCE between the distance distributions (p > 0.05)

and a more extensive selection of plots is here.

 

 

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